---
title: Insights - CFD and scale-down notes | p4b
description: "CFD and scale-down notes from p4b: mixing times, gradients and what cells experience in large bioreactors - and how to bring production-scale conditions into the lab."
image: https://meet.p4b.io/hubfs/raw_assets/public/p4b/images/og-default.png
---

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Products

[**pDS inserts**Large-scale conditions in your lab bioreactor](https://meet.p4b.io/pds) [**Advanced CFD**Gradients, lifelines and cell experiences](https://meet.p4b.io/cfd) [**DREAM-bio**Find the best geometry for your bioreactor](https://meet.p4b.io/dream-bio) [**Ambr® 250 vs. 2,000 L**Interactive CFD comparison of the mixing](https://meet.p4b.io/compare)

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Insights

# Notes from the simulation lab

What we learn while simulating and scaling down bioreactors - mixing, gassing, validation and the occasional surprise.

![pDS inserts next to Ambr 250 vessels](https://meet.p4b.io/hubfs/website/pds-family.webp)

White paper · CHO demonstration case

## Large-scale conditions in a 1 L lab bioreactor

How a reactor designed by generative AI recreates the gradients of a 10,000 L scale in a 1 L vessel - and what they do to lactate and mAb titer in a CHO process. 4 pages, free.

[Download the white paper](https://share-eu1.hsforms.com/1Iz-e9dcFQYax4uBfRa8fiw2dmt7m)

Get in touch

## Let's find out how your process reacts to scale

Tell us your system and target scale - we come back with a proposal for your insert set.

[Request a quote](https://meet.p4b.io/contact#quote)[Book a 30-min call](https://meet.p4b.io/contact#meeting)

![Lena Achleitner](https://meet.p4b.io/hs-fs/hubfs/website/team/lena-avatar.webp?width=84&height=84&name=lena-avatar.webp)

**Lena Achleitner**Senior Bioprocess Engineer, Key Account Manager[lena.achleitner@p4b.io](mailto:lena.achleitner@p4b.io)

### Get new insights by email

CFD results, case studies and new insert systems when we publish them. Unsubscribe any time.

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Scale reliably. Develop faster.  
Digital and 3D-printed technologies for bioprocessing.

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#### Products

- [pDS inserts](https://meet.p4b.io/pds)
- [Advanced CFD](https://meet.p4b.io/cfd)
- [DREAM-bio](https://meet.p4b.io/dream-bio)
- [Request a quote](https://meet.p4b.io/contact#quote)

#### Company

- [About us](https://meet.p4b.io/about)
- [Case studies](https://meet.p4b.io/case-studies)
- [Insights](https://meet.p4b.io/insights)
- [Events](https://meet.p4b.io/events)
- [Contact](https://meet.p4b.io/contact)

#### Contact

**Office & deliveries**  
p4b GmbH  
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1190 Vienna, Austria

[+43 677 61062225](tel:+4367761062225)  
[office@p4b.io](mailto:office@p4b.io)

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